Peptide mediators are important physiological regulators. This exercise investigates the physiology and pharmacology of peptide mediators in learning and memory (cognition). In this exercise, you will research the pharmacology of a particular peptide mediator involved in cognition, and design a theoretical drug that interferes with this peptide pathway to improve cognition. You will then prepare a poster that presents the pharmacology of your peptide, and the drug you have designed.
During tutorial time. Each one will then be allocated a peptide by the tutor(Galanin).
Your task is to design a drug that will (theoretically) act on the physiological pathway (production, action or termination) of your peptide and improve cognition (i.e. a new ‘smart pill’). You can work as a group to research your peptide, however each student needs to design their drug (and prepare their poster) individually.
- Research your peptide and determine its physiology and pharmacology (production, transport, physiological action and termination). Your primary source for research should be peer-reviewed biomedical science literature which you can search for using PubMed(Links to an external site.)Links to an external site..
- Decide on a likely point of intervention in this peptide pathway, that you predict will improve cognition
- Create a name for your new drug.
- Prepare a 1 page poster advertising your new drug. Your poster must include the following required elements:
- The name of your new drug.
- The peptide pathway your drug acts on.
- The mechanism of action for your drug (use a flow diagram).
- A catchy marketing slogan.
- Submit your poster via the online submission link on the course website by 9am Tuesday May
- Research the physiological pathway of a specific peptide mediator.
- Apply your knowledge of pharmacology to design a theoretical drug that interacts with a peptide pathway to produce a desired biological effect.
- Communicate information about your peptide pathway and new drug in a clear, engaging, and accurate manner.